S.No. | API | Intermediate Name | CAS # |
1 | Apixaban | 3-morpholino-1-(4-(2-oxopiperidin-1-yl) phenyl)-5, 6- dihydropyridin-2(1H)-one | 545445-44-1 |
2 | Apixaban | (Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono) acetate | 27143-07-3 |
3 | Apixaban | 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one | 503615-03-0 |
4 | Apixaban | Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin- 1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | 503614-91-3 |
5 | Apremilast | 3-Acetamidophthalic anhydride | 6296-53-3 |
6 | Apremilast | (S)-1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethanamine | 608141-42-0 |
7 | Aripiprazole | 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-uinolinone | 129722-34-5 |
8 | Atorvastatin Calcium | Tert-Butyl(4R,6R)-2-[[[6-(2-4-fluorophenyl)-5- isopropyl-3-phenyl-4-(phenylcarbamoyl) pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3dioxan-4-yl]acetate | 125971-95-1 |
9 | Clopidogrel | Methyl-(4,5,6,7-tetrahydro-5-thieno [3,2-c] pyridyl) (2-chlorophenyl) acetate hydrochloride | 144750-52-7 |
10 | Clopidogrel | S(+)-2-(2-Chloropheny)-6,7-dihydrothieno (3,2- C)pyridine-5(4H)-acetic acid methyl ester camphorsulfonate | 120202-68-8 |
11 | Dabigatran Etexilate Mesylate | N-[3-Amino-4-(methyl amino)benzoyl]-N-2-pyridinyl- ethyl ester | 212322-56-0 |
12 | Dabigatran Etexilate Mesylate | 2-(4-Cyanophenylamino) Acetic acid | 42288-26-6 |
13 | Dabigatran Etexilate Mesylate | Ethyl 3-(2-(((4-cyanophenyl) amino) methyl)-1-methyl-
N-pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido) propanoate |
211915-84-3 |
14 | Dabigatran Etexilate Mesylate | Ethyl 3-2-(4-amidinophenylamino) methyl)-1-methyl- N-(pyridin-2yl)-1H-benzo[d]imidazole-5-carboxamido) propanoate. | 429658-95-7 |
15 | Dabigatran Etexilate Mesylate | Ethyl 3-{[(2-{[(4-{N’-[(Hexyloxy) carbonyl] carbamimidoyl} phenyl) amino]methyl}-l-methyl- lH- benzimidazol-5-yl)carbonyl] (2-yridinyl)amino}propanoate | 211915-06-9 |
16 | Dabigatran Etexilate Mesylate | Ethyl 3-[[2-[[4-(E)-N1-hexyloxycarbonyl carbamimidoyl] aniline] methyl]-1- methylbenzimidazole-5-carbonyl] pyridin-2-ylamino] propanoate | 1408238-36-7 |
17 | Deferasirox | 2-(2-Hydroxy phenyl)benz(e)[1,3]-oxazin-4-one. | 1218-69-5 |
18 | Deferasirox | 4-hydrazino benzoic Acid | 619-67-0 |
19 | Doxazosin Mesylate | N-(1,4-Benzodioxan-2-carbonyl)piperazine | 70918-00-2 |
20 | Doxazosin Mesylate | 4-Amino-2-chloro-6,7-dimethoxyquinazoline | 23680-84-4 |
21 | Eletriptan Hydrobromide | (R)-5-Bromo-3-((1-methyl-2-pyrrolidinyl) methyl] -1H-indole | 143322-57-0 |
22 | Esomeprazole magnesium | 6-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2- pyridinyl)methyl]sulfinyl]-1H-benzimidazole potassium salt (1:1) | 161796-84-5 |
23 | Fluvoxamine Maleate | 5-Methoxy-1-[4-(trifluoromethyl) phenyl]-1-pentanone | 61718-80-7 |
24 | Labetalol HCL | 5-Bromoacetyl Salicylamide | 73866-23-6 |
25 | Lamotrigine | 2-(2,3-Dichlorophenyl)-2-(guanidinylamino)acetonitrile | 84689-20-3 |
26 | Lansoprazole | 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy) pyridin-2-yl] methyl]thio]-1H-benzimidazole | 103577-40-8 |
27 | Linagliptin | (R)-tert-butyl 1-(7-but-2-ynyl)-3-methyl-1-((4- methylquinazoin-2-yl) methyl)-2,6-dioxo-2,3,6,7- tetrahydro-1H-purin-8-yl)piperidin-3-yl carbamate. | 668273-75-4 |
28 | Mirabegron | 4-Nitrophenethylamine hydrochloride | 29968-78-3 |
29 | Mirabegron | 2-Aminothiazol-4-acetic acid | 29676-71-9 |
30 | Mirabegron | 2-Aminothiazol-4-acetic acid Hydrochloride | 66659-20-9 |
31 | Mirabegron | (R)-2-Hydroxy-N-(4-nitrophenethyl)-2- phenylacetamide | 521284-19-5 |
32 | Mirabegron | (alpha R)-alpha –***2- (4-nitrophenyl) ethyl+ amino+ methyl]benzene methanol Hydrochloride | 521284-21-9 |
33 | Mirabegron | (alpha R)-alpha –***2-(4-nitrophenyl)ethyl+ amino]methyl] benzene methanol 27 (1R) -2-[[2-(4-aminophenyl | 223673-34-5 |
34 | Mirabegron | (R) -2-[2-(4-amino-phenyl) ethylamino] -1-phenyl- ethanol HCl | 521284-22-0 |
35 | Omeprazole | 5-methoxy-2-[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl]thio]-1H -benzimidazole. | 73590-85-9 |
36 | Oseltamivir
Phosphate |
Ethyl (3R, 4S, 5S)- 4,5-epoxy-3-(1-ethyl-propoxy) cyclohex-1-ene-1-carboxylate | 204254-96-6 |
37 | Oseltamivir
Phosphate |
Ethyl (3R,4R,5S)-4-acetamido-5-azido-3-(1-
ethylpropoxy)-1 -cyclohexene-1-carboxylate |
204255-06-1 |
38 | Oseltamivir Phosphate | Ethyl (3R, 4S, 5S)-4, N-acetyl (1,1-dimethyl ethyl)
amino-5-N,N-diallylamino-3- (1-ethylpropoxy)-1- cyclohexene-1-carboxylate hydrochloride |
651324-08-2 |
39 | Pantoprazole
Sodium Sesquihydrate |
5-Difluoromethoxy-2-{[(3, 4-dimethoxy-pyridin-2- yl)methyl]thio}-1H -benzimidazole. | 102625-64-9 |
40 | Paroxetine HCL | (3S,4R)-4-(4-Fluorophenyl)-3-hydroxymethyl-1- methylpiperidine | 105812-81-5 |
41 | Perampanel | 5′-bromo-1′-phenyl-[2,3′-bipyridin]-6′(1’H)-one | 381248-06-2 |
42 | Pirfenidone | 5-Methylpyridin-2(1H)-one | 1003-68-5 |
43 | Prasurgrel | 2-Bromo-2-(2-fluorophenyl)-1-cyclopropylethanone | 204205-33-4 |
44 | Prasurgrel | 5, 6,7,7a-Tetrahydrothieno(3,2-c]pyridine-2(4H)-one hydrochloride | 115473-15-9 |
45 | Raloxifene | 4-(2-Piperidin-1-yl-ethoxy)benzoic acid hydrochloride | 1246815-60-0 |
46 | Raloxifene | 6-Methoxy-2-(4-methoxyphenyl) benzo [b] thiophene | 63675-74-1 |
47 | Raltegravir | Methyl 2-[[(benzyloxy) carbonyl] amino]-1- methylethyl]- 1methyl-5-hydroxy-6-Oxo-1, 6-dihydroxy pyrimidine-4-carboxylate. | 888504-27-6 |
48 | Raltegravir | Benzyl [1-[4-[[(4-fluorobenzyl) amino]carbonyl] -5- hydroxy-1-methyl- 6-oxo-1,6-dihydropyrimidin-2-yl] -1-methylethyl] carbamate | 518048-02-7 |
49 | Raltegravir | 5-Methyl-1,3,4-oxadiazole-2-carboxilic acid potassium salt. | 888504-28-7 |
50 | Ranolazine | 1-[N-(2,6-Dimethylphenyl)carbamoyl methyl] piperazine | 5294-61-1 |
51 | Ranolazine | 1-(2-Methoxyphenoxy)-2,3-epoxypropane | 2210-74-4 |
52 | Rivaroxaban | 4-(4-aminophenyl)morpholin-3-one | 438056-69-0 |
53 | Rivaroxaban | S(+) -Glycidyl phthamide | 161596-47-0 |
54 | Rivaroxaban | 5-chlorothiophene-2-carboxylic acid | 24065-33-6 |
55 | Rivaroxaban | 2-[(2R)-2-Hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl] amino} propyl]-1H-isoindole-1,3(2H)-dione | 446292-07-5 |
56 | Rivaroxaban | (S)-2-((2-oxo-3-(4-(3-oxo-morpholino)phenyl) oxazolidin-5-yl)methyl)isoindoline- 1,3-dione | 446292-08-6 |
57 | Rivaroxaban | 4 -[4-[(5S)-5-(Aminomethyl)-2-oxo-3- oxazolidinyl]phenyl]-3-morpholinone Hydrochloride | 898543-06-1 |
58 | Sofosbuvir | N-((s)-(2,3,4,5,6-Pentafluorophenoxy) phenoxyphosphinyl)-L-alanine methylethyl ester | 1334513-02-8 |
59 | Tadalafil | 1,2,3,4-Tetrhydro-2-chloroacetyl-1-(3,4-methylene dioxyphenyl)-9H-pyrido [3,4-B] indole-3- carobxylate CAS No. | 171489-59-1 |
60 | Teneligliptin | 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl) piperazine | 401566-79-8 |
61 | Teneligliptin | (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1- pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester | 401564-36-1 |
62 | Tolvaptan | 7-Chloro-1-[2-methyl-4-[(2-methylbenzoyl) amino]benzoyl]-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine. | 137973-76-3 |
63 | Tolvaptan | 7-chloro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-one | 160129-45-3 |
64 | Valacyclovir Hydrochloride Monohydrate | 2-[(2-amino-1,6-dihydro-6-oxo-9H -purin-9-yl) methoxy] ethyl N-[(phenylmethoxy)carbonyl]-L-valinate | 124832-31-1 |
65 | Valgancyclovir | N -(benzyloxycarbonyl)-L-valine-2-[(2-amino-1,6- dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester | 194154-40-0 |
66 | Valgancyclovir | Ganciclovir Monoacetate | 88110-89-8 |
67 | Voriconazole | 1-(2,4-Difluorophenyl)-2-(1H-1 ,2,4-triazole-1-yl) ethanone | 86404-63-9 |
68 | Voriconazole | 4-chloro-6-ethyl-5-fluoropymidine | 137234-74-3 |
69 | Diclofenac Sodium | 2,6 Dichloro Diphenyl Amine | 15307-93-4 |
70 | Diclofenac Sodium | N chloro acetyl 2 6 dichloro diphenyl amine | 15308-01-7 |
71 | Diclofenac Sodium | 1-(2,6-DICHLOROPHENYL)-2-INDOLINONE | 15362-40-0 |
72 | Teneligliptin | 1-(3-Methyl-1-phenyl-1H-pyrazol-5-yl) piperazine | 401566-79-8 |
73 | Teneligliptin | (2S)-4-Oxo-2-(3-thiazolidinylcarbonyl)-1pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester | 401564-36-1 |
74 | Itopride | Veratric Acid | 93-07-2 |
75 | Sitagliptin | Keto Sitagliptin | 764667-65-4 |
76 | Sitagliptin | 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine HCl | 762240-92-6 |
77 | Labetalol | 5-bromoacetylsalicylamide | 40187-51-7 |